East Coast Road which starts at about 25 kms from Chennai and leads to Mahabalipuram area (60 kms from Chennai) has some excellent destination resorts [List].  

Tirupati India's most visited temple is also accessible from Chennai (165 kms - 4 hours) and therefore an obvious choice for a religious getaway. For a list of hotels at Tirupati click here.

Another Option even for a 2 night stay is Pondicherry. Its 160 kms South of Chennai on East Coast Road (3 hours) but the drive itself and French heritage of Pondicherry and destination resorts around it can be a good option. [List of Pondicherry Hotels and Resorts ].

Chennai itself has a few high end Hotels that can be opted for a luxurious weekend and exploring Chennai city and its famous Marina Beach [List of Chennai Hotels].

Short Break and Holiday Ideas / Itineraries Ex-Chennai

Mahabalipuram - Pondicherry (Beach - Heritage) (Ex-Chennai)

Tamilnadu Heritage Itinerary (Beach - Religious - Heritage) - (Ex-Chennai)

Tamilnadu Religious Itinerary (Religious - Heritage)

- Itinerary also suited for honeymooners.